Thursday, October 20, 2016

Acarbose


Pronunciation: AY-kar-bose
Generic Name: Acarbose
Brand Name: Precose


Acarbose is used for:

Treating type 2 diabetes. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.


Acarbose is a glucosidase inhibitor. It works by slowing down the enzyme that turns carbohydrates into glucose. This results in a smaller rise in blood sugar levels following a meal.


Do NOT use Acarbose if:


  • you are allergic to any ingredient in Acarbose

  • you have blockage of the stomach or bowel, or you are at risk of these problems

  • you have inflammatory bowel disease, colon ulcers, or long-term (chronic) stomach or bowel problems that interfere with digestion or nutrient absorption

  • you have cirrhosis of the liver

  • you have diabetic ketoacidosis (high ketone levels) or severe kidney problems

Contact your doctor or health care provider right away if any of these apply to you.



Before using Acarbose:


Some medical conditions may interact with Acarbose. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have stomach or bowel problems, liver problems or unexplained abnormal liver function tests, or kidney problems

Some MEDICINES MAY INTERACT with Acarbose. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Acarbose

  • Calcium channel blockers (eg, verapamil), corticosteroids (eg, prednisone), diuretics (eg, hydrochlorothiazide), estrogen, isoniazid, nicotinic acid, oral contraceptives (birth control pills), phenothiazines (eg, chlorpromazine), phenytoin, sympathomimetics (eg, pseudoephedrine), or thyroid hormones (eg, levothyroxine) because they may increase the risk of high blood sugar levels

  • Insulin or sulfonylureas (eg, glyburide) because they may increase the risk of low blood sugar levels

  • Oral neomycin because it may increase the risk of Acarbose's side effects

  • Digoxin because its effectiveness may be decreased by Acarbose

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acarbose may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Acarbose:


Use Acarbose as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Acarbose by mouth at the start (with the first bite) of each main meal.

  • If you also take charcoal or digestive enzyme preparations (eg, amylase, pancreatin), ask your doctor or pharmacist how to take them with Acarbose.

  • Temporary insulin therapy may be necessary during stressful periods (such as fever, infection, surgery, or trauma). Talk with your doctor if any of these occur.

  • If you miss a dose of Acarbose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acarbose.



Important safety information:


  • Proper diet and exercise are important in order to lose weight and keep it off. Follow the diet and exercise program given to you by your health care provider.

  • Diabetes patients - Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher than they should be and you take Acarbose exactly as prescribed, tell your doctor.

  • Tell your doctor or dentist that you take Acarbose before you receive any medical or dental care, emergency care, or surgery.

  • Carefully follow the regular testing of urine or blood glucose schedules given to you by your health care provider.

  • When other diabetes medicines are used with Acarbose, low blood sugar levels may occur. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you hungrier. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. This will raise your blood sugar level quickly. Because Acarbose prevents the breakdown of table (cane) sugar, be sure to use glucose (dextrose), not sugar or fruits, to treat symptoms of low blood sugar. Contact your health care provider right away if these symptoms occur.

  • Lab tests, including blood glucose, glycosylated hemoglobin levels, and liver function, may be performed while you use Acarbose. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Acarbose should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Acarbose while you are pregnant. It is not known if Acarbose is found in breast milk. Do not breast-feed while taking Acarbose.


Possible side effects of Acarbose:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Bloating; diarrhea; gas; nausea; stomach pain; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe stomach pain; symptoms of liver problems (eg, dark urine; pale stools; unusual or severe nausea, tiredness, or loss or appetite; yellowing of the skin or eyes).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Acarbose side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; gas; stomach pain or discomfort.


Proper storage of Acarbose:

Store Acarbose below 77 degrees F (25 degrees C) in a tightly sealed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acarbose out of the reach of children and away from pets.


General information:


  • If you have any questions about Acarbose, please talk with your doctor, pharmacist, or other health care provider.

  • Acarbose is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Acarbose. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Acarbose resources


  • Acarbose Side Effects (in more detail)
  • Acarbose Use in Pregnancy & Breastfeeding
  • Drug Images
  • Acarbose Drug Interactions
  • Acarbose Support Group
  • 0 Reviews for Acarbose - Add your own review/rating


  • Acarbose Prescribing Information (FDA)

  • Acarbose Monograph (AHFS DI)

  • Acarbose Professional Patient Advice (Wolters Kluwer)

  • acarbose Concise Consumer Information (Cerner Multum)

  • acarbose Advanced Consumer (Micromedex) - Includes Dosage Information

  • Precose Prescribing Information (FDA)



Compare Acarbose with other medications


  • Diabetes, Type 2

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